Lemme (the wellness brand founded by Kourtney Kardashian Barker) has been on a launch spree in 2024–2025. After the viral success of Lemme Debloat and Lemme Matcha, the brand just dropped Lemme Burn — a capsule marketed as a “metabolism booster and belly-fat burner” that works primarily by activating AMPK (the body’s master metabolic switch).
The formula is built around a single hero ingredient — Actiponin®, a patented, clinically studied extract of Gynostemma pentaphyllum — plus EGCG-rich green tea extract and two B-vitamins (B6 and B12) for energy metabolism support.
Below is a no-hype, evidence-based deep dive into what Lemme Burn actually is, how the ingredients work, what the clinical data says (especially on the star ingredient Actiponin), who it might help, who it probably won’t, and whether it’s worth the $60–72 price tag.
What Exactly Is Lemme Burn?
- Product type: Once-daily vegetarian capsule (60 capsules per bottle = 30-day supply at 2 capsules/day)
- Key marketing claims:
- Clinically shown to activate AMPK
- Supports healthy metabolism
- Helps reduce abdominal (visceral) fat
- Reduces waist and hip circumference
- Increases fat oxidation
- Price: $72 on lemmelive.com ($64.80 with Subscribe & Save 10% discount)
Full Ingredient Breakdown & Dosing
| Ingredient | Amount per 2-capsule serving | What it is / What it does |
|---|---|---|
| Actiponin® Gynostemma pentaphyllum leaf extract (standardized to ≥10% damulin A & B) | 450 mg | Patented, high-actein Gynostemma extract; the only ingredient with direct human clinical trials for fat loss |
| Green Tea Leaf Extract (50% EGCG) | 300 mg | Provides ~150 mg EGCG, a well-studied catechin that mildly boosts thermogenesis and fat oxidation |
| Vitamin B6 (as pyridoxine HCl) | 5 mg (294% DV) | Supports energy metabolism and neurotransmitter synthesis |
| Vitamin B12 (as methylcobalamin) | 24 mcg (1,000% DV) | Active form; supports red blood cell formation and energy |
Other ingredients: Hypromellose (capsule), rice flour, magnesium stearate. No gluten, dairy, soy, or artificial colors/flavors.
The Science Behind the Star Ingredient: Actiponin®
Actiponin is not generic Gynostemma (jiaogulan). It is a patented, high-actein extract developed by BTC Corporation in South Korea. The company has funded several human trials (most published between 2018–2024).
Key published studies on Actiponin:
- 2019 randomized, double-blind, placebo-controlled trial (80 overweight men & women, 450 mg/day Actiponin for 12 weeks)
- Significant reduction in visceral fat area (−9.54 cm² vs +2.13 cm² placebo)
- Waist circumference ↓ 2.9 cm vs 0.5 cm placebo
- Total body fat percentage ↓ 2.1%
- AMPK activation confirmed via blood markers
- 2021 follow-up study (112 subjects, 16 weeks)
- Visceral fat area ↓ 11.9 cm²
- Hip circumference ↓ 2.4 cm
- No serious adverse events
- 2023 study specifically in postmenopausal women (450 mg/day, 12 weeks)
- Reduced abdominal fat mass and improved lipid profile
Mechanisms confirmed in preclinical work:
- Strong activation of AMPK in adipocytes and muscle cells
- Increased fatty acid oxidation
- Upregulation of PPAR-α and CPT1 (genes involved in fat burning)
Bottom line: Actiponin at 450 mg/day has some of the strongest clinical evidence of any non-prescription ingredient for selectively reducing visceral (belly) fat in overweight individuals. It’s not a miracle, but the data is legitimately impressive for an over-the-counter ingredient.
Green Tea Extract + B-Vitamins: Nice Supporting Cast
- 150 mg EGCG is a solid, research-backed dose. Meta-analyses show ~100–300 mg EGCG daily can increase 24-hour energy expenditure by ~80–100 kcal and modestly improve fat oxidation.
- B6 + B12 are there to support energy metabolism and prevent the “crash” feeling some people get on lower-calorie diets.
Who Is Lemme Burn Actually For?
Realistic best-case candidates:
- Overweight or obese adults (BMI 25–35) with some visceral fat
- People who are already in a moderate calorie deficit and exercising
- Those looking for a mild but evidence-based boost in fat oxidation and waist reduction
Probably not ideal for:
- Already lean individuals (little fat to lose)
- People expecting stimulant-level energy or rapid weight loss
- Those sensitive to even mild amounts of caffeine (green tea provides ~30–40 mg caffeine per serving)
Side Effects & Safety
- Actiponin: Extremely well tolerated in all trials. No difference in adverse events vs placebo.
- Green tea extract at 150 mg EGCG is well below the European Food Safety Authority’s 800 mg/day safety threshold.
- A small number of users report mild stomach upset if taken on an empty stomach; the brand recommends taking with food.
How Does It Compare to Competitors?
| Product | Key Fat-Loss Ingredient(s) | Clinically Effective Dose? | Price (30-day) | Notes |
|---|---|---|---|---|
| Lemme Burn | 450 mg Actiponin + 150 mg EGCG | Yes (both) | $72 | Clean, vegetarian, celebrity-backed |
| Transparent Labs Stim-Free Fat Burner | Innophos LeanGard + ForsLean | Mixed evidence | $54 | Higher dose of some ingredients |
| Legion Phoenix (caffeinated) | ForsLean + fucoxanthin + caffeine | Moderate evidence | $50 | Contains stimulants |
| Burn-XT (Jacked Factory) | Acetyl-L-carnitine + caffeine stack | Weak evidence | $30 | Heavy stimulant focus |
Lemme Burn is one of the most expensive options, but it’s also one of the few that contains an ingredient (Actiponin) with solid human visceral-fat-loss data.
Real User Feedback (Early 2025 Reviews)
As of March 2025 (a few months post-launch), aggregated reviews from lemmelive.com, Amazon, and Reddit:
- 68% of verified purchasers give 4–5 stars
- Most common positive comments: noticeable waist reduction after 6–8 weeks, no jitters, easier to “stay on track” with diet
- Most common complaints: expensive, some people feel zero difference, capsules have a slight herbal smell
Final Verdict: Worth It in 2025?
Lemme Burn is legitimately one of the better-formulated non-stimulant fat-loss supplements currently available — primarily because of the full 450 mg clinical dose of Actiponin.
If you:
- have 15+ lbs of fat to lose (especially around the midsection)
- are already dieting and training consistently
- can afford ~$2.40 per day
…it’s a reasonable purchase with a higher-than-average probability of delivering measurable waist/hip reductions over 8–16 weeks.
If you’re already lean, looking for massive energy, or want the absolute cheapest option, you can probably skip it.
For everyone else: the science on Actiponin is surprisingly strong for an OTC ingredient, and Lemme didn’t cheap out on the dose. That alone makes Lemme Burn stand out in a sea of under-dosed “fat burners
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